Schild H H, Günther R, Thelen M
Department of Radiology, Johannes Gutenberg University Hospital and Medical School, Mainz, Germany.
J Vasc Interv Radiol. 1994 Mar-Apr;5(2):321-5. doi: 10.1016/s1051-0443(94)71494-9.
The effectiveness of transrenal ureteral occlusion was evaluated.
Transrenal ureteral occlusions were performed in 83 ureters of 76 patients. Thirty-one ureters were occluded with use of tissue adhesive, which was secured in place with Gianturco coils in 21. Fifty-two ureters were occluded by means of silicone-filled, detachable latex balloons. Average follow-up was 3.6 months (range, 1 week to 38 months) for patients treated with the tissue adhesive and 7.9 months (range, 1 week to 61 months) for patients treated with the detachable balloons.
Seventeen (55%) of the 31 ureters occluded with tissue adhesive and 36 (69%) of the 52 ureters occluded with detachable balloons were permanently sealed after a single procedure. In 30 ureters, the occlusion procedure had to be repeated. The average duration of temporarily effective occlusions was 2.5 weeks when tissue adhesive was used and 19.5 weeks with detachable balloons. Complications were observed in 10 (7%) of 138 interventions. Only four of these were considered significant: two perforations occurred at the ureteropelvic junction, septicemia was seen after one procedure, and damage to a small intrarenal artery necessitated selective embolization in one patient.
In selected patients, transrenal ureteral occlusion can effectively and safely interrupt urinary flow toward the bladder. Detachable balloons were superior to tissue adhesive as an occluding agent.
评估经肾输尿管闭塞术的有效性。
对76例患者的83条输尿管进行了经肾输尿管闭塞术。31条输尿管使用组织粘合剂闭塞,其中21条用Gianturco线圈固定在位。52条输尿管通过填充硅胶的可分离乳胶球囊闭塞。使用组织粘合剂治疗的患者平均随访3.6个月(范围1周至38个月),使用可分离球囊治疗的患者平均随访7.9个月(范围1周至61个月)。
使用组织粘合剂闭塞的31条输尿管中有17条(55%),使用可分离球囊闭塞的52条输尿管中有36条(69%)在单次手术后实现永久性封闭。30条输尿管的闭塞操作需要重复进行。使用组织粘合剂时,临时有效闭塞的平均持续时间为2.5周,使用可分离球囊时为19.5周。138次干预中有10次(7%)观察到并发症。其中只有4次被认为较为严重:输尿管肾盂交界处发生2次穿孔,1次手术后出现败血症,1例患者因肾内小动脉受损需要进行选择性栓塞。
在选定的患者中,经肾输尿管闭塞术能够有效且安全地中断尿液向膀胱的流动。作为闭塞剂,可分离球囊优于组织粘合剂。