Janeĉek J, Zícha B, Otoupal P, Kalousová V, Svantnerová V
Vet Med (Praha). 1975 Dec;20(12):733-9.
Some new findings regarded the dynamics of the changes in the white component of peripheral blood, particularly at early intervals in the case of three clinically differing doses of ionizing radiation were obtained. At the highest dose early nonspecific leucocytosis was recorded only six hours after the exposure. Significant neutrophili occurred in the case of all three doses beginning from the sixth hour. With the highest dose it had the shortest duration and highest values, and at the smallest dose the opposite was the case. In the case of the highest dose leucopenia sets in after 24 hours, and in the case of the other doses not until after 36 hours. Lymphopenia appears already after 6 hours, the consequences according to the doses, however, manifest themselves only after 12 hours. In all three groups leucopenia and lymphopenia have a constant character. It was confirmed that the changes in the white blood component were the most typical response to the exposure to ionizing radiation, and orientation and special criteria have been found for the estimation of the consequences of the forms of irradiation on the basis of numerical changes of leucocytes, lymphocytes, and neutrophilic granulocytes within 72 hours after the exposure.
获得了一些关于外周血白细胞成分变化动态的新发现，特别是在三种临床不同剂量电离辐射情况下的早期阶段。在最高剂量下，仅在照射后6小时记录到早期非特异性白细胞增多。从第6小时开始，所有三种剂量均出现明显的中性粒细胞增多。最高剂量时，其持续时间最短且值最高，而最小剂量时情况相反。最高剂量时，24小时后出现白细胞减少，其他剂量则直到36小时后才出现。淋巴细胞减少在6小时后就已出现，但其后果根据剂量不同，仅在12小时后才显现出来。在所有三组中，白细胞减少和淋巴细胞减少都具有持续性。已证实白细胞成分的变化是对电离辐射暴露最典型的反应，并且已找到基于暴露后72小时内白细胞、淋巴细胞和中性粒细胞的数值变化来评估不同照射形式后果的方向和特殊标准。
