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[正常心肌、冠状动脉供血不足及心肌梗死病例的酶组织化学比较研究(作者译)]

[Comparative enzyme-histochemical studies on normal myocardium, in cases of coronary insufficiency and myocardial infarction (author's transl)].

作者信息

Roesch L H, Kuch J, Knieriem H J

出版信息

Virchows Arch A Pathol Anat Histol. 1976 Apr 5;370(1):21-39. doi: 10.1007/BF00427308.

Abstract

Comparative histochemical studies with Tetrazolium salt solutions were performed on 25 human and 3 canine hearts. After perfusion of whole hearts with Tetrazolium solutions extensive unstained areas were observed which proved to be artefacts, since they reacted positively after incubation of the heart-slices. The perfusion method of Lichtig, Feldman, Glagov and Wissler (1973) which was proposed for macroscopic and microscopic diagnosis of ischemic cardiac lesions was not found to be suitable for the identification of microcirculatory disturbances. The usual incubation method, however, proved to be useful for the macroscopic localization of recent myocardial infarcts.

摘要

用四氮唑盐溶液对25颗人心脏和3颗犬心脏进行了比较组织化学研究。在用四氮唑溶液对整个心脏进行灌注后,观察到广泛的未染色区域,这些区域被证明是人为现象,因为在心脏切片孵育后它们呈阳性反应。Lichtig、Feldman、Glagov和Wissler(1973年)提出的用于缺血性心脏病变宏观和微观诊断的灌注方法,并不适用于识别微循环障碍。然而,常规的孵育方法被证明对近期心肌梗死的宏观定位是有用的。

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