van Erkel A R, van Gils A P, Lequin M, Kruitwagen C, Bloem J L, Falke T H
Department of Diagnostic Radiology and Nuclear Medicine, Leiden University Hospital, The Netherlands.
J Comput Assist Tomogr. 1994 May-Jun;18(3):432-8. doi: 10.1097/00004728-199405000-00017.
Because the distinction between adenomas and nonadenomas of the adrenal gland is essential, we investigated which of the following parameters--size, CT attenuation values, MRI signal intensity ratios on T1- and T2-weighted sequences, calculated T2 relaxation times, or T2 relaxation time ratios--provides better discrimination.
We compared these parameters in 44 adrenal masses of 37 patients by means of the Student t test and receiver operating characteristics (ROC) analyses.
Only size, CT attenuation values, and signal intensity ratios on T2-weighted MR images of adenomas showed a significant difference from those of nonadenomas. With use of ROC analysis, CT demonstrated a significantly larger area under the curve compared to size and T2 signal intensity ratios, indicating superior performance.
We found attenuation values on non-contrast-enhanced CT to be the best method in discriminating adrenal adenomas from nonadenomas. Adrenal masses with CT attenuation values below 15 HU warrant no further investigations.
由于肾上腺腺瘤与非腺瘤的鉴别至关重要,我们研究了以下参数——大小、CT衰减值、T1加权和T2加权序列上的MRI信号强度比、计算得到的T2弛豫时间或T2弛豫时间比——哪一个能提供更好的鉴别效果。
我们通过学生t检验和受试者操作特征(ROC)分析,比较了37例患者44个肾上腺肿块的这些参数。
仅腺瘤的大小、CT衰减值以及T2加权MR图像上的信号强度比与非腺瘤存在显著差异。通过ROC分析,与大小和T2信号强度比相比,CT显示曲线下面积显著更大,表明其性能更优。
我们发现非增强CT的衰减值是鉴别肾上腺腺瘤与非腺瘤的最佳方法。CT衰减值低于15 HU的肾上腺肿块无需进一步检查。