Oommen S T, Natu M V, Mahajan M K, Kadyan R S
Department of Pharmacology, Christian Medical College, Ludhiana, Punjab, India.
Int J Lepr Other Mycobact Dis. 1994 Mar;62(1):32-6.
Pedal edema as a possible adverse effect of clofazimine therapy in leprosy was first reported in 1990. Raasch, et al. reported their lymphangiographic findings on ten patients who had clinical lepromatous leprosy in 1969. None of these patients had been on clofazimine therapy. Our study, therefore, was designed to assess the changes that might be seen in the lymphatic system of patients treated with clofazimine for the management of leprosy. Our findings are compared with those of Raasch and his colleagues.
1990年首次报道了氯法齐明治疗麻风病可能产生的不良反应——足部水肿。1969年,拉施等人报告了他们对10例临床瘤型麻风病患者的淋巴管造影检查结果。这些患者均未接受氯法齐明治疗。因此,我们的研究旨在评估接受氯法齐明治疗麻风病的患者淋巴系统可能出现的变化。我们将研究结果与拉施及其同事的结果进行了比较。