Zanella E
Cattedra di Patologia Speciale Chirurgica e Propedeutica Clinica, Università degli Studi di Roma Tor Vergata.
Minerva Endocrinol. 1993 Dec;18(4):165-7.
Indications for the surgical removal of autonomous nodule are mainly based upon the failure of therapeutical options. The histological definition may be advantageous for detecting the rare but possible association between autonomous goiter and carcinoma of the thyroid. In personal experience, based on 176 hyperfunctioning goiter (among which there were 40 cases of autonomous nodules) 6 carcinomas of the gland were observed, 2 of these were associated with autonomous nodules. The extension of thyroidectomy is related to the size of the adenomas considering the incidence of postoperative complications, very low for this type of surgery. Surgical treatment of autonomous nodules of the thyroid is a low risk surgery and is therefore suitable for the treatment of this disease.
自主性结节手术切除的指征主要基于治疗方案的失败。组织学定义可能有助于发现自主性甲状腺肿与甲状腺癌之间罕见但可能存在的关联。根据个人经验，在176例功能亢进性甲状腺肿（其中有40例自主性结节）中，观察到6例甲状腺癌，其中2例与自主性结节相关。考虑到术后并发症的发生率，甲状腺切除术的范围与腺瘤大小有关，这类手术的并发症发生率非常低。甲状腺自主性结节的手术治疗是一种低风险手术，因此适合治疗这种疾病。
