Nilsson P
Lunds Universitet, Centrum för samhällsmedicin.
Nord Med. 1994;109(5):151-3.
A number of pathological conditions have been associated with increased insulin resistance. Reduced insulin sensitivity may occur even under normal physiological conditions, and is more pronounced in men than in women. The aetiology of type II diabetes, lipid disorders and hypertension is characterised by reduced insulin sensitivity. A new theory which has been advanced to explain these pathological conditions is the occurrence of intra-uterine growth retardation due to fetal malnutrition. The elucidation of these events may affect treatment in the future.
许多病理状况都与胰岛素抵抗增加有关。即使在正常生理条件下，胰岛素敏感性也可能降低，且在男性中比在女性中更为明显。II型糖尿病、脂质紊乱和高血压的病因特征是胰岛素敏感性降低。为解释这些病理状况而提出的一种新理论是，由于胎儿营养不良导致子宫内生长迟缓。对这些事件的阐明可能会影响未来的治疗。
