Bujía J
Department of Otorhinolaryngology, Head and Neck Surgery, Ludwig-Maximilians University of Munich, Germany.
Ann Plast Surg. 1994 Mar;32(3):261-5.
Transplantation of uncrushed and crushed cartilage has assumed a role of great importance in reconstructive surgery of the nose. There are many divergent and contradictory opinions with regard to the outcome of cartilage, so we formulated this study to assess the functional state of chondrocytes in severely and mildly crushed as well as uncrushed and cut cartilage. Crushing and cutting leads to necrosis of a part of the graft. More of the cartilage cells are irreversibly damaged by crushing. The proportion of surviving cells, depending on the severity of crushing, is between 10 and 30%. In contrast to this, after cutting most of the cells remained viable and were able to proliferate. It is concluded that crushed cartilage not only remains unviable but is also not able to produce new cartilage; therefore, it will be subjected to resorption processes and not be useful for the reconstruction of parts of the nasal skeleton that support mechanical stress.
完整无损和受到挤压的软骨移植在鼻整形手术中已占据极为重要的地位。关于软骨移植的结果存在许多不同且相互矛盾的观点，因此我们开展了本研究，以评估严重挤压、轻度挤压以及完整无损和切割后的软骨中软骨细胞的功能状态。挤压和切割会导致移植物的一部分发生坏死。更多的软骨细胞会因挤压而受到不可逆的损伤。存活细胞的比例取决于挤压的严重程度，在10%至30%之间。与此形成对比的是，切割后大多数细胞仍保持活力并能够增殖。得出的结论是，受到挤压的软骨不仅无法存活，而且也无法生成新的软骨；因此，它将经历吸收过程，对承受机械应力的鼻骨架部分的重建并无用处。
