Raharimalala L, Lepers J P, Lepers-Rason M D, Rabarison P, Ramambanirina L, Roux J
Arch Inst Pasteur Madagascar. 1993;60(1-2):60-4.
According to pharmaco-sensitivity studies, about 20% of local Plasmodium falciparum strains showed a certain degree of resistance to chloroquine. No resistance of R3 type has never been observed. During this whole period, the decrease of sensitivity phenomenon remains stable. Because of its remarkable action on parasitemia and fever, chloroquine remains the best antimalaria in simple malarial attacks in madagascar.
根据药敏研究，当地约20%的恶性疟原虫菌株对氯喹呈现出一定程度的耐药性。从未观察到R3型耐药性。在整个这一时期，敏感性下降现象保持稳定。由于氯喹对疟原虫血症和发热有显著作用，在马达加斯加治疗单纯性疟疾发作时，氯喹仍然是最佳抗疟药物。
