Guillou L, Nordback P, Gerber C, Schneider R P
University Institute of Pathology, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland.
Arch Pathol Lab Med. 1994 May;118(5):568-71.
We present a case of ductal adenocarcinoma originating in a heterotopic pancreas in a 60-year-old patient. The tumor developed at the esophagogastric junction in a hiatal hernia. The nontumoral pancreatic tissue showed ductal cystic dystrophy with enclosed stones, as well as lesions of chronic pancreatitis with metaplastic changes. The perigastric lymph nodes and the liver contained metastatic deposits. Malignant transformation in an ectopic pancreas is exceptional. To our knowledge, this would be the first case occurring in such a location. We review the literature on the subject and discuss the theory of the tumors arising in an aberrant pancreas.
我们报告一例60岁患者，其导管腺癌起源于异位胰腺。肿瘤发生于食管胃交界处的食管裂孔疝内。非肿瘤性胰腺组织显示导管囊性营养不良伴结石形成，以及伴有化生改变的慢性胰腺炎病变。胃周淋巴结和肝脏有转移灶。异位胰腺发生恶性转化极为罕见。据我们所知，这是首例发生在该部位的病例。我们回顾了关于该主题的文献，并讨论了起源于异位胰腺的肿瘤的理论。
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