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[黑腹果蝇中同源异型突变触角足和芒状触角的相互作用]

[Interaction of homoeotic mutations Antennapedia and aristapedia in Drosophila melanogaster].

作者信息

Bulyzhenkov V E, Ginter E K, Ivanov V I

出版信息

Genetika. 1975;11(11):27-33.

PMID:819324
Abstract

Expression of a number of mutant alleles of Antennapedia and aristapedia loci in pairwise combination of the type Antp ssa/+ssa was compared with their expression in initial Antp and ssa stocks. Marked mutual enhancement of homoeotic action of the genes studied was observed up to the formation of well developed antennal legs consisting of coxae, trochanter, femurs, tibiae and five-segment tarsi in some flies (especially, Antp49 ssa/+ssa). Antennapedia-specificity (rather than aristapedia) of the interaction was found. Cellular basis of action and interaction of homoeotic genes is discussed.

摘要

将触角足(Antennapedia)和芒状触角(aristapedia)基因座的多个突变等位基因以Antp ssa/+ssa类型进行两两组合后的表达情况,与它们在初始的Antp和ssa品系中的表达进行了比较。观察到所研究基因的同源异型作用有明显的相互增强,在一些果蝇中(特别是Antp49 ssa/+ssa)甚至形成了发育良好的触角腿,其由基节、转节、股骨、胫骨和五节跗节组成。发现这种相互作用具有触角足特异性(而非芒状触角特异性)。文中还讨论了同源异型基因作用及相互作用的细胞基础。

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