Byrne P, Onyekwuluje T
Department of Obstetrics and Gynaecology, Walsgrave Hospital, Coventry, UK.
Ir Med J. 1994 Mar-Apr;87(2):54-5.
Gemeprost (Cervagem), a synthetic PGE1 prostaglandin analogue was used to induce labour in 20 patients with second trimester intra uterine fetal death. The mean induction abortion interval was 13.8 hours; 17 of the 20 patients delivered within 24 hours. In 17 cases the placenta was retained and the uterus was evacuated under general anaesthesia. Nausea was noted in five (25%) patients, vomiting in two (10%) and diarrhoea in three (15%). No serious side-effects were encountered.
吉美前列素(Cervagem),一种合成的PGE1前列腺素类似物,被用于诱导20例孕中期宫内死胎患者分娩。平均引产至流产间隔时间为13.8小时;20例患者中有17例在24小时内分娩。17例患者出现胎盘滞留,在全身麻醉下清空子宫。5例(25%)患者出现恶心,2例(10%)呕吐,3例(15%)腹泻。未出现严重副作用。