Mastroianni A, Coronado O, Manfredi R, Chiodo F
Istituto Malattie Infettive, Università degli Studi di Bologna.
Minerva Med. 1994 Mar;85(3):117-9.
Neurological complications represent one of the most important causes of morbidity and mortality in patients with HIV infection or AIDS. The peripheral nervous system is frequently involved in different stages of HIV disease, and the etiopathogenetic mechanisms are various. Idiopathic peripheral facial nerve palsy (Bell's palsy) has been considered by several Authors as one of the possible neurologic complications of HIV infection, mainly described in the early stages. As a matter of fact when facial palsy onsets in the late stages of the disease, when there is a severe immunodeficiency, usually is secondary to opportunistic infections, polyradiculopathy, or tumors involving the nervous system. To our knowledge, in the current literature there are few clinical studies reporting facial palsy associated to HIV infection. Since 1986 till 1992 three HIV infected patients with Bell's palsy have come to our observation. All three of them were asymptomatic (CDC II) and in one of them was the first clinical manifestation indicating HIV infection. The palsy in this patient and those reported by others was self-limiting with a good prognosis.
神经并发症是艾滋病毒感染或艾滋病患者发病和死亡的最重要原因之一。外周神经系统经常在艾滋病毒疾病的不同阶段受累，其发病机制多种多样。特发性周围性面神经麻痹（贝尔麻痹）被多位作者认为是艾滋病毒感染可能的神经并发症之一，主要在疾病早期出现。事实上，当面神经麻痹在疾病晚期、存在严重免疫缺陷时发作，通常继发于机会性感染、多发性神经根病或累及神经系统的肿瘤。据我们所知，目前文献中很少有关于与艾滋病毒感染相关的面神经麻痹的临床研究。从1986年到1992年，我们观察到3例感染艾滋病毒且患有贝尔麻痹的患者。他们三人都无症状（疾病控制与预防中心II级），其中一人的贝尔麻痹是表明艾滋病毒感染的首个临床表现。该患者以及其他报告的患者的麻痹均为自限性，预后良好。
