Katz P G, Greenstein A, Midha M, Marcelino V, Jones L K, Wong E S
Division of Urology, Hunter Holmes McGuire VA Medical Center, Virginia Commonwealth University, Richmond.
Urology. 1994 Jun;43(6):792-6. doi: 10.1016/0090-4295(94)90137-6.
Recurrent urinary tract infections are common in spinal-cord-injured patients. Our study was designed to evaluate the association of bacteria colony counts, white blood cell (WBC) count, and antibody-coated bacteria analyzed in urethral and prostatic samples in hospitalized spinal-cord-injured patients with recurrent urinary tract infections.
Thirty-three patients were studied and 4 noninfected patients served as controls; 17 patients were paraplegic and 20 were quadriplegic. Mean patient age was 34.8 years and mean follow-up period was ninety-three days. During the surveillance period, 19 of the 33 patients had relapsing infections (same organism), while 14 had reinfections (new organism). A modified Foley catheter was used to seal the bladder neck, so that urethral and prostatic samples could be obtained.
Bacteria colony counts and WBC counts did not correlate with relapsing infection. However, significantly more patients with relapsing infection (8/19) had antibody-coated bacteria in their prostatic fluid than patients with reinfection (1/13) (P < 0.05).
The presence of antibody-coated bacteria in prostatic fluid is associated with relapsing urinary tract infections and not with reinfection.
复发性尿路感染在脊髓损伤患者中很常见。我们的研究旨在评估住院脊髓损伤患者复发性尿路感染时，尿道和前列腺样本中细菌菌落计数、白细胞（WBC）计数以及抗体包被细菌之间的关联。
对33例患者进行了研究，4例未感染患者作为对照；17例患者为截瘫，20例为四肢瘫。患者平均年龄为34.8岁，平均随访期为93天。在监测期内，33例患者中有19例出现复发性感染（同一病原体），而14例出现再感染（新病原体）。使用改良的Foley导尿管封闭膀胱颈，以便获取尿道和前列腺样本。
细菌菌落计数和WBC计数与复发性感染无关。然而，复发性感染患者（8/19）前列腺液中抗体包被细菌的比例显著高于再感染患者（1/13）（P<0.05）。
前列腺液中抗体包被细菌的存在与复发性尿路感染相关，而与再感染无关。
