Wynder E L
MMW Munch Med Wochenschr. 1975 Aug 1;117(31):1265-72.
There is evidence of the epidemiological role of nutrition in the pathogenesis of various forms of human diseases; several components of nutrition are known to have a carcinogenic effect in man. In terms of epidemiology, however, alcoholism is most important which through the development of malnutrition enhances the risk of carcinosis of the upper gastrointestinal tract particularly in smokers. Nutritional deficiences have an influence on the incidence of cancer of the stomach, cervix and thyroid. Overnutrition favours the development of certain forms of cancer such as malignant diseases of the colon, pancreas, kidney, mamma, ovary, endometrium and prostate.
有证据表明营养在多种人类疾病的发病机制中具有流行病学作用;已知营养的几个成分对人类有致癌作用。然而,从流行病学角度来看,酗酒最为重要,它通过导致营养不良增加了上消化道癌症的风险,尤其是在吸烟者中。营养缺乏会影响胃癌、宫颈癌和甲状腺癌的发病率。营养过剩则有利于某些形式癌症的发展,如结肠癌、胰腺癌、肾癌、乳腺癌、卵巢癌、子宫内膜癌和前列腺癌。