Darling C F, Byrd S E, Reyes-Mugica M, Tomita T, Osborn R E, Radkowski M A, Allen E D
Department of Radiology, Children's Memorial Hospital, Chicago, IL 60614.
AJNR Am J Neuroradiol. 1994 Mar;15(3):435-44.
To assess MR and pathologic characteristics of childhood intracranial meningiomas, comparing the radiographic findings with those observed in adult intracranial meningiomas.
Clinical records, MR and CT scans, and histology of eight children with intracranial meningiomas presenting for a period of 7.5 years were retrospectively reviewed.
Boys equaled girls but predominated from ages 4 to 11 years. The ages ranged from 4 to 18 years. Two patients had radiation-induced meningiomas. Two children had multiple lesions; neither had neurofibromatosis. All solitary lesions were supratentorial. Other characteristics included: dural-based attachment (n = 6); large size (> 5 cm) (n = 4); cystic components (n = 3); and intraventricular location (n = 1). Histologic subtypes were: meningothelial (n = 4); transitional (n = 3); and fibroblastic (n = 1). Preoperative diagnoses of meningiomas were made in six cases based on overall imaging characteristics.
Diagnosis of childhood intracranial meningiomas does not differ from that of adults radiographically, with the exception of larger tumor sizes.
评估儿童颅内脑膜瘤的磁共振成像(MR)和病理特征,将影像学表现与成人颅内脑膜瘤的表现进行比较。
回顾性分析7.5年间8例儿童颅内脑膜瘤患者的临床记录、MR和CT扫描以及组织学检查结果。
男童与女童数量相等,但4至11岁年龄段男童占优势。年龄范围为4至18岁。2例患者为放射诱导性脑膜瘤。2例儿童有多个病灶;均无神经纤维瘤病。所有单发病灶均位于幕上。其他特征包括:以硬脑膜为基底附着(n = 6);体积较大(> 5 cm)(n = 4);有囊性成分(n = 3);位于脑室内(n = 1)。组织学亚型为:脑膜内皮型(n = 4);过渡型(n = 3);纤维母细胞型(n = 1)。6例根据整体影像学特征术前诊断为脑膜瘤。
除肿瘤体积较大外,儿童颅内脑膜瘤的影像学诊断与成人无异。