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胃十二指肠溃疡的非切除手术。I. 病理生理原理(作者译)

[Non-resecting surgery for gastroduodenal ulcer. I. Pathophysiological principles (author's transl)].

作者信息

Bauer H, Andersson S, Okukubo F, Kahn F, Schmidt G, Holle F

出版信息

MMW Munch Med Wochenschr. 1976 Jun 11;118(24):767-76.

PMID:819804
Abstract

Selective proximal vagotomy with pyloroplasty is a method which permits ulcers to be operated on with less morphological and pathophysiological disturbances than is possible with any other method. After ingestion, a reactive yet reduced acid secretion is still possible through the gastrin stimulus. The retained vagal antral release of gastrin seems to be without importance to the denervated delomorphous cells. Side effects of this type of vagotomy are small. The disturbances of motility and evacuation which also occur here can easily be corrected by an additional pyloroplasty suitable in shape and function.

摘要

选择性近端迷走神经切断术加幽门成形术是一种手术方法,与其他任何方法相比,该方法能在形态学和病理生理学干扰较小的情况下对溃疡进行手术。摄入食物后,通过胃泌素刺激仍可产生反应性但减少的胃酸分泌。保留的迷走神经对胃窦胃泌素的释放似乎对去神经的变形细胞不重要。这种迷走神经切断术的副作用较小。在此处出现的运动和排空障碍可通过形状和功能合适的附加幽门成形术轻松纠正。

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