Babaniyi O
Ministry of Health, Ilorin, Kwara State, Nigeria.
West Afr J Med. 1993 Oct-Dec;12(4):218-22.
A comprehensive review of the EPI sentinel surveillance data for Kwara State, Nigeria was conducted for the years 1982--1987 to evaluate programme impact. Measles vaccination coverage moved up from 26 percent in 1984 to between 54 percent and 58 percent in Ilorin, LGA, Kwara State, Nigeria from 1986 to 1988. During the period of review, the annual number of measles cases and the incidence rate of measles reported by the surveillance system has continued to fall from 1985, the year the revised EPI programme was launched in Ilorin LGA. There was infact a forty-one percent reduction in measles incidence in Ilorin LGA in 1987, but measles is still an important cause of preventable morbidity and mortality in the area. Twenty-two percent of reported measles cases occurred in children under nine months of age, children who are younger than the recommended age of vaccination. Two results expected in a partially vaccinated population, a reduction in measles incidence greater than the level of vaccination coverage and a shift in the age-distribution of measles to older children, have not been observed. Measles control in Ilorin LGA will require a vaccination coverage higher than 58 percent. Also, given the age-specific risk of measles infection there, a measles vaccine that would be effective when given before nine months of age would be an important element in controlling measles transmission. Because the epidemiology of measles in Ilorin is a likely consequence of its urban environment, such a vaccine would represent a significant advance toward the control of measles in urban Africa.(ABSTRACT TRUNCATED AT 250 WORDS)
对尼日利亚夸拉州1982 - 1987年扩大免疫规划(EPI)哨点监测数据进行了全面审查,以评估该规划的影响。1984年,尼日利亚夸拉州伊洛林地方政府区(LGA)的麻疹疫苗接种覆盖率为26%,1986年至1988年升至54%至58%之间。在审查期间,自1985年伊洛林地方政府区启动修订后的扩大免疫规划以来,监测系统报告的麻疹病例年度数量和麻疹发病率持续下降。事实上,1987年伊洛林地方政府区的麻疹发病率下降了41%,但麻疹仍是该地区可预防发病和死亡的重要原因。报告的麻疹病例中有22%发生在9个月以下的儿童中,这些儿童未达到推荐的疫苗接种年龄。在部分接种疫苗的人群中预期会出现的两个结果,即麻疹发病率的下降幅度大于疫苗接种覆盖率,以及麻疹发病年龄分布向大龄儿童转移,并未观察到。伊洛林地方政府区的麻疹控制需要高于58%的疫苗接种覆盖率。此外,鉴于该地区存在特定年龄的麻疹感染风险,一种在9个月龄前接种有效且能控制麻疹传播的麻疹疫苗将是一个重要因素。由于伊洛林的麻疹流行病学可能是其城市环境导致的结果,这样一种疫苗将代表非洲城市地区麻疹控制方面的重大进展。(摘要截选至250字)