Tumwine J K
Department of Paediatrics and Child Health, University of Zimbabwe Medical School, Avondale, Harare.
East Afr Med J. 1991 Sep;68(9):694-701.
In the rural district of Chimanimani in Zimbabwe, the Expanded Programme on Immunisation (EPI) which started in January 1982 has achieved measles coverage of between 50 and 80% in the 12-23 months age group, from 1984 to 1988, through 65 outreach centres, and 15 static health centres serving 93985 people in 119 villages. Facility based data as well as community based surveys have failed to show serious measles transmission in children under nine months of age, a common observation in high population density urban areas in Africa. Instead there has been a reduction in measles incidence and age distribution of measles has shifted to older children. The lowest measles incidence rate of 0.8 per 100 children occurred in the 0-5 months age group and the highest incidence rate of 4.0 per 100 children in the 48-59 months of age group. Only 7.9% of measles cases occurred in children under nine months of age. The high vaccination coverage rates were made possible by the post-independence government commitment, community involvement and dedicated staff. Our observations support the current one-dose 9 months minimum age measles vaccination policy for the low density rural areas in the developing countries.
在津巴布韦的奇马尼马尼农村地区,始于1982年1月的扩大免疫规划(EPI),在1984年至1988年期间,通过65个外展中心和15个为119个村庄的93985人服务的固定健康中心,在12至23个月龄组中实现了50%至80%的麻疹疫苗接种覆盖率。基于设施的数据以及社区调查均未显示9个月以下儿童中有严重的麻疹传播情况,这在非洲人口密度高的城市地区是常见现象。相反,麻疹发病率有所下降,麻疹的年龄分布已转向年龄较大的儿童。麻疹发病率最低为每100名儿童0.8例,出现在0至5个月龄组;最高发病率为每100名儿童4.0例,出现在48至59个月龄组。只有7.9%的麻疹病例发生在9个月以下的儿童中。独立后政府的承诺、社区参与和敬业的工作人员使得高疫苗接种覆盖率成为可能。我们的观察结果支持发展中国家低密度农村地区目前的单剂量、9个月最低年龄的麻疹疫苗接种政策。