Eiam-ong S, Kurtzman N A
Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock 79430.
Miner Electrolyte Metab. 1994;20(1-2):72-80.
Bone is the largest repository base in the body. Prolonged acid retention requires continuous buffering of acid if the organism is to survive. This paper discusses the role of bone buffering under both normal and altered conditions of acid-base homeostasis. We place particular emphasis on the roles of PTH and vitamin D in this process. We also discuss bone abnormalities in renal tubular acidosis and chronic renal failure.
骨骼是人体最大的储备库。如果机体要存活，长时间的酸潴留需要持续的酸缓冲。本文讨论了在酸碱平衡的正常和改变条件下骨骼缓冲的作用。我们特别强调甲状旁腺激素（PTH）和维生素D在此过程中的作用。我们还讨论了肾小管性酸中毒和慢性肾衰竭中的骨骼异常。
