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[支气管哮喘患者支气管炎症变化及高反应性的纤维支气管镜评估]

[The fiber bronchoscopic evaluation of the bronchial inflammatory changes and hyperreactivity in bronchial asthma patients].

作者信息

Gerasin V A, Palamarchuk G F, Kizela A P

出版信息

Ter Arkh. 1994;66(3):15-9.

PMID:8202843
Abstract

Bronchofibroscopic bronchial examination detected inflammation-induced changes in the bronchi in the form of mucosal thickening (edema), small masses of the sputum and occasional hyperemia in the majority of the examinees with bronchial asthma. In combination with bronchoalveolar lavage, bronchofibroscopy provides diagnosis of bronchial hyperreactivity basing on determination of segmentary bronchial stenosis in response to salt solution instillation. The degree of this stenosis can evidence the degree of hyperreactivity of the bronchi. Bronchofibroscopic signs of bronchial hyperreactivity appear more distinctly in asthma aggravations, in severe run of the disease, in pronounced inflammation.

摘要

纤维支气管镜支气管检查发现,在大多数支气管哮喘患者中,支气管出现了炎症引起的变化,表现为黏膜增厚(水肿)、少量痰液积聚以及偶尔的充血。结合支气管肺泡灌洗,纤维支气管镜检查通过测定滴注盐溶液后节段性支气管狭窄情况来诊断支气管高反应性。这种狭窄程度可证明支气管高反应性的程度。支气管高反应性的纤维支气管镜征象在哮喘加重期、疾病严重发作期及明显炎症时表现得更为明显。

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[The fiber bronchoscopic evaluation of the bronchial inflammatory changes and hyperreactivity in bronchial asthma patients].[支气管哮喘患者支气管炎症变化及高反应性的纤维支气管镜评估]
Ter Arkh. 1994;66(3):15-9.
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[The effect of the Russian inhalant glucocorticosteroid budesonide on bronchial inflammation and hyperreactivity during the long-term treatment of bronchial asthma patients].
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[Bronchial inflammation in asthma. Evaluation by bronchial biopsies].[哮喘中的支气管炎症。通过支气管活检进行评估]
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Asthma, bronchial hyperreactivity and mediator release in children with birch pollinosis. ECP and EPX levels are not related to bronchial hyperreactivity.桦树花粉症患儿的哮喘、支气管高反应性及介质释放。嗜酸性粒细胞阳离子蛋白(ECP)和嗜酸性粒细胞过氧化物酶(EPX)水平与支气管高反应性无关。
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Airway mast cells and eosinophils correlate with clinical severity and airway hyperresponsiveness in corticosteroid-treated asthma.在接受皮质类固醇治疗的哮喘患者中,气道肥大细胞和嗜酸性粒细胞与临床严重程度及气道高反应性相关。
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Assessment of airway inflammation: an overview.
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