Borisova A M, Khoroshilova N V, Pinegin B V, Eremina O F, Simonova A V, Kulakov A V, Golubeva N M, Dykhanov I I
Ter Arkh. 1994;66(3):46-50.
The paper reports the results of ribomunil trial in chronic bronchitis (CB) patients who suffered from frequent exacerbations. The drug was found to act primarily on a phagocytic component of the immunity and local immunity of the respiratory mucosa. Because of its vaccine-like effect, ribomunil administration is most beneficial in CB remission. Ribomunil treatment results in reduction of the number and duration of CB exacerbations, of the scope of antibacterial therapy.
该论文报告了核糖核酸免疫调节剂(Ribomunil)在频繁病情加重的慢性支气管炎(CB)患者中的试验结果。发现该药物主要作用于免疫的吞噬成分以及呼吸道黏膜的局部免疫。由于其类似疫苗的作用,服用核糖核酸免疫调节剂对慢性支气管炎的缓解最为有益。核糖核酸免疫调节剂治疗可减少慢性支气管炎病情加重的次数和持续时间以及抗菌治疗的范围。