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[系统性硬化症中肺动脉高压的临床功能特征]

[The clinico-functional characteristics of pulmonary arterial hypertension in systemic scleroderma].

作者信息

Mirrakhimov M M, Moldotashev I K, Bakeeva M E, Shmidt G F

出版信息

Ter Arkh. 1994;66(3):67-71.

PMID:8202858
Abstract

Electro-, phono-, echo-, and Doppler echocardiography, bulbar biomicroscopy were performed in 54 SS patients aged 18-64. Mean pulmonary arterial pressure (PP) was determined at Doppler echocardiography on Toshiba SSH-40A unit according to techniques developed by M. M. Mirrakhimov et al. in 1989. The diagnosis of pulmonary hypertension (PH) was made in PP above 18 mm Hg. A close relationship was found between SS history and PH registration. With growing SS duration, PH severity increases, microcirculatory disorders progress. Main PH risk factors in SS patients are believed SS duration, activity, Raynaud's syndrome presentation. Doppler echocardiography can effectively diagnose PH in its subclinical stage, is noninvasive.

摘要

对54名年龄在18至64岁的干燥综合征(SS)患者进行了心电图、心音图、超声心动图、回声心动图和多普勒超声心动图检查以及眼球生物显微镜检查。根据M.M.米拉基莫夫等人于1989年开发的技术,使用东芝SSH - 40A设备通过多普勒超声心动图测定平均肺动脉压(PP)。肺动脉高压(PH)的诊断标准为PP高于18 mmHg。发现SS病史与PH的确诊之间存在密切关系。随着SS病程的延长,PH严重程度增加,微循环障碍进展。SS患者主要的PH危险因素被认为是SS病程、活动情况、雷诺综合征表现。多普勒超声心动图能够在PH的亚临床阶段有效诊断,且为非侵入性检查。

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