Bach A, Böttiger B W
Klinik für Anästhsiologie, Ruprecht-Karls-Universität Heidelberg.
Zentralbl Chir. 1994;119(4):268-75.
Contamination of parenterally applied fluids by bacterial and particulate material may contribute to the development of sepsis, multiple organ failure, and adult respiratory distress syndrome. 0.2 microns in-line filters are effective in reducing bacteria and foreign matter in the infused fluids. The rate of thrombophlebitis was demonstrated to be significantly reduced by in-line filtration. However, to date there is no definite evidence from clinical studies that these filters are effective in reducing overall morbidity and mortality. Furthermore the use of in-line filters reduces waste material and required nursing time, because the infusion systems have to be replaced every 96 hours as opposed to 24 hours without filters. In conclusion, use of 0.2 microns in-line filters in infusion therapy is cost effective and may enhance patients' safety.
经肠道外途径输注的液体被细菌和颗粒物质污染可能会促使败血症、多器官功能衰竭及成人呼吸窘迫综合征的发生。0.2微米的在线过滤器能有效减少输注液体中的细菌和异物。研究表明，在线过滤可显著降低血栓性静脉炎的发生率。然而，迄今为止，尚无临床研究的确切证据表明这些过滤器能有效降低总体发病率和死亡率。此外，使用在线过滤器可减少废料并节省护理时间，因为输液系统每96小时更换一次，而未使用过滤器时则每24小时更换一次。总之，在输液治疗中使用0.2微米的在线过滤器具有成本效益，且可能提高患者安全性。
