Sano R, Nakamura T, Kanayama R, Okuyama T, Koike Y
Department of Otolaryngology, Yamagata University School of Medicine, Japan.
Acta Otolaryngol Suppl. 1994;511:135-7. doi: 10.3109/00016489409128317.
Unilateral vestibular disorders were induced in 3 cats by means of the injection of a small amount of sodium hydroxide into the middle ear, and vestibulo-ocular responses (VOR) to various kinds of pendular stimulation were investigated at 1 week and at 1, 2, 3, 4, and 5 months after the operation. The pendular rotation test was performed at frequencies of 0.025, 0.1, 0.25 and 0.5 Hz, and peak velocities of 50, 100, 150, and 200 degrees/s, and the directional preponderance of the VOR gain (DP%) was measured using a computer. DP% 1 week after the operation was still very high at each frequency and velocity of the stimulation. On the other hand, DP% more than 1 month after the operation had decreased markedly, although it increased with an increase in the velocity of stimulation at all frequencies except at 0.5 Hz, and DP% at a velocity of 200 degrees/s was still high even 5 months later. This suggests that high velocity pendular stimulation should be used to detect unilateral vestibular disorders.
通过向3只猫的中耳注射少量氢氧化钠诱导单侧前庭疾病，并在术后1周以及术后1、2、3、4和5个月研究对各种摆动刺激的前庭眼反射（VOR）。摆动旋转测试在0.025、0.1、0.25和0.5Hz的频率以及50、100、150和200度/秒的峰值速度下进行，并且使用计算机测量VOR增益的方向优势（DP%）。术后1周，在每个刺激频率和速度下DP%仍然非常高。另一方面，术后1个月以上DP%明显下降，尽管除0.5Hz外，在所有频率下DP%都随着刺激速度的增加而增加，并且即使在5个月后，200度/秒速度下的DP%仍然很高。这表明应使用高速摆动刺激来检测单侧前庭疾病。
