Brindley P J
Tropical Health Program, Queensland Institute of Medical Research, Bancroft Centre, Brisbane, Australia.
Acta Trop. 1994 Mar;56(2-3):213-31. doi: 10.1016/0001-706x(94)90064-7.
It is usual for people to be infected for some period in life with parasitic worms, which may cause morbidity or even kill. Anthelmintics are used for the treatment and control of the human helminthiases, since no vaccines are yet available. Despite the widespread use of these compounds, drug resistance has become apparent only with antischistosomal chemotherapy, in contrast to the situation with other anti-infective agents in human medicine and with veterinary anthelmintics, where resistance is widespread. This paper reviews research on drug resistance in human helminthiasis with emphasis on schistosomicidal drugs.
人们在生活中的某个阶段感染寄生虫是很常见的，这些寄生虫可能会导致发病甚至死亡。由于目前尚无疫苗，驱虫药被用于治疗和控制人类蠕虫病。尽管这些化合物被广泛使用，但与人类医学中的其他抗感染药物和兽医驱虫药广泛存在耐药性的情况不同，耐药性仅在抗血吸虫化疗中变得明显。本文综述了人类蠕虫病耐药性的研究，重点是抗血吸虫药物。
