Holbert T R
Am J Obstet Gynecol. 1994 Jun;170(6):1699-703; discussion 1703-4.
The objective of this study was to determine the value of screening transvaginal ultrasonography for the evaluation of endometrial or ovarian abnormalities in asymptomatic postmenopausal women in a private gynecology office at the time of yearly examination.
All postmenopausal women who were seen for yearly examination between June 1, 1991, and June 1, 1993, underwent screening transvaginal ultrasonographic examinations that I performed. Women who had any pelvic symptoms or who were premenopausal were excluded from the study group.
During the 24 months of this study 478 women were screened. One case of early ovarian carcinoma was diagnosed, one case of superficial adenocarcinoma of the endometrium was discovered, and 28 other ovarian cysts were seen. All women with cystic changes in the ovaries underwent testing for serum CA 125 levels, and follow-up ultrasonography was done at 1 and 3 months. Ovaries were removed if the CA 125 level was elevated, if the cyst became larger, or if the patient desired. No additional ovarian carcinomas were found in those women who had cysts discovered on ultrasonography and who subsequently had the ovaries removed.
Screening transvaginal ultrasonography examinations were well received by all patients, there was no significant associated discomfort, the scans required minimal time, and a significant number of abnormalities were discovered, including two early carcinomas. I believe that when transvaginal ultrasonography is available in an office setting, where it can be performed at no or very low cost, routine screening of postmenopausal women is a valuable addition to the yearly examination.
本研究的目的是确定在一家私立妇科诊所进行年度检查时,经阴道超声筛查对无症状绝经后妇女子宫内膜或卵巢异常评估的价值。
1991年6月1日至1993年6月1日期间接受年度检查的所有绝经后妇女均接受了我所进行的经阴道超声筛查检查。有任何盆腔症状或处于绝经前的妇女被排除在研究组之外。
在本研究的24个月期间,对478名妇女进行了筛查。诊断出1例早期卵巢癌,发现1例子宫内膜浅表腺癌,还发现了28个其他卵巢囊肿。所有卵巢有囊性改变的妇女均检测了血清CA 125水平,并在1个月和3个月时进行了超声随访。如果CA 125水平升高、囊肿变大或患者有意愿,则切除卵巢。在超声检查发现有囊肿并随后切除卵巢的妇女中未发现其他卵巢癌。
经阴道超声筛查检查受到所有患者的好评,没有明显的相关不适,扫描所需时间最短,并且发现了大量异常,包括2例早期癌症。我认为,当在诊所环境中可进行经阴道超声检查且成本为零或非常低时,对绝经后妇女进行常规筛查是年度检查的一项有价值的补充。