Fang S Y
Department of Otolaryngology, National Cheng Kung University, Tainan, Taiwan, Republic of China.
Ann Otol Rhinol Laryngol. 1994 Jun;103(6):439-43. doi: 10.1177/000348949410300604.
To evaluate the secretory element transformation of maxillary sinus mucosa after endoscopic sinus surgery (ESS), I enrolled 20 patients. Five normal antral mucosae were used as controls, and 15 antral mucosae were investigated according to pathologic and secretory patterns. The post-ESS mucosa was evaluated at the 16th week, when gross recovery appeared. Specimens from the rear wall of the antrum were observed under a scanning electron microscope (x2,000). A significant decrease of goblet cells and increase of glands was illustrated in the sinusitis cases, especially the polypoid and purulent groups. In post-ESS cases, the number of goblet cells is about the same as in controls, but the number of gland openings is higher. My conclusions were that 1) the repair of the antral mucosa requires more time than gross recovery and 2) post-ESS follow-up should be longer than 16 weeks to prevent recurrence.
为评估鼻内镜鼻窦手术（ESS）后上颌窦黏膜的分泌成分变化，我纳入了20例患者。选取5例正常鼻窦黏膜作为对照，对15例鼻窦黏膜根据病理和分泌模式进行研究。在术后第16周，即大体恢复时，对ESS后的黏膜进行评估。取窦腔后壁标本在扫描电子显微镜下（放大2000倍）观察。结果显示，鼻窦炎病例中杯状细胞显著减少，腺体增多，尤其是息肉样和化脓性组。在ESS术后病例中，杯状细胞数量与对照组相近，但腺体开口数量更多。我的结论是：1）鼻窦黏膜的修复比大体恢复需要更长时间；2）ESS术后随访应超过16周以预防复发。
