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[康氏立克次体所致脑膜脑炎。病因病理、临床及诊断方面]

[Meningoencephalitis due to Rickettsia conorii. Etiopathological, clinical and diagnostic aspects].

作者信息

Marcos Dolado A, Sánchez Portocarrero J, Jiménez Madridejo R, Pontes Navarro J C, García Urra D

机构信息

Servicio de Neurología, Hospital Universitario San Carlos, Madrid.

出版信息

Neurologia. 1994 Feb;9(2):72-5.

PMID:8204253
Abstract

Boutonneuse fever (BF) is usually considered to be a benign rickettsiosis. However, severe presentations, resembling Rocky Mountain spotted fever, have been reported. There are few neurological complications, except in serious forms of the disease. We present a case of meningoencephalitis in a male adult suffering from BF, and we review the clinical, etiopathogenic and diagnostic aspects among the cases previously reported. We conclude that BF encephalitis would have the following characteristics: a) they mostly affect elderly males; b) they cause altered consciousness level, headaches and low rate of meningeal signs; c) absence of "tâche noir"; d) cerebrospinal fluid with slight pleocytosis and/or increased level of proteins, and normal glucose values; e) computerized tomography without significative changes, and f) high rate of morbidity and mortality. We emphasize that we should consider BF in the differential diagnosis of our environmental encephalitis.

摘要

纽扣热(BF)通常被认为是一种良性立克次体病。然而,已有报道称其存在类似落基山斑疹热的严重表现。除了疾病的严重形式外,神经系统并发症很少见。我们报告一例患有BF的成年男性脑膜脑炎病例,并回顾先前报道病例中的临床、病因和诊断方面。我们得出结论,BF脑炎具有以下特征:a)主要影响老年男性;b)导致意识水平改变、头痛和脑膜刺激征发生率低;c)无“黑色斑点”;d)脑脊液有轻度细胞增多和/或蛋白质水平升高,葡萄糖值正常;e)计算机断层扫描无明显变化;f)发病率和死亡率高。我们强调,在对环境性脑炎进行鉴别诊断时应考虑BF。

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