Nighorn A, Qiu Y, Davis R L
Department of Cell Biology, Baylor College of Medicine, Houston, TX 77030.
Comp Biochem Physiol Biochem Mol Biol. 1994 May;108(1):1-9. doi: 10.1016/0305-0491(94)90157-0.
The genetic dissection of learning and memory in Drosophila is two decades old. Recently, a great deal of progress has been made towards isolating new mutants as well as towards a better understanding of the originally isolated ones. This paper reviews the recent developments in the understanding of the structure and function of the gene identified by the first and best-characterized of these mutants, the Drosophila dunce mutant.
对果蝇学习与记忆的遗传学剖析已有20年历史。最近,在分离新突变体以及更好地理解最初分离出的突变体方面取得了很大进展。本文回顾了在理解这些突变体中第一个且特征描述最完善的突变体——果蝇“笨蛋”突变体所鉴定基因的结构和功能方面的最新进展。