用灭活结核杆菌甲醇提取残余物部分（MER）处理对C57B1小鼠肿瘤3LL同基因植入物自发性肺转移发展的影响。
Effect of treatment with the methanol extraction residue fraction of killed tubercle bacilli (MER) on the development of spontaneous pulmonary metastases from syngeneic implants of tumor 3LL in C57B1 mice.
作者信息
Treves A J, Cohen I R, Feldman M, Weiss D W
出版信息
Isr J Med Sci. 1976 Apr-May;12(4-5):384-7.
Treatment of C57B1 mice with the methanol extraction residue fraction of killed tubercle bacilli (MER) shortly before or after surgical removal of a syngeneic implant of lung carcinoma 3LL reduced the incidence of spontaneous, fatally progressing pulmonary metastases in a large number of instances. Under certain conditions, the protective action of MER was pronounced and statistically significant. Small quantities of MER (0.2 mg) were optimally effective, when administered i.p. two days before or one day after excision of the initial implant.
在手术切除同基因肺癌3LL植入物之前或之后不久，用灭活结核杆菌的甲醇提取残余物部分（MER）处理C57B1小鼠，在许多情况下可降低自发性致命性进展性肺转移的发生率。在某些条件下，MER的保护作用显著且具有统计学意义。当在切除初始植入物前两天或后一天腹腔注射时，少量的MER（0.2毫克）效果最佳。
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