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Suppression by thyrotropin-releasing hormone (TRH) of growth hormone release induced by arginine and insulin-induced hypoglycemia in man.

作者信息

Maeda K, Kato Y, Chihara K, Ohgo S, Iwasaki Y

出版信息

J Clin Endocrinol Metab. 1976 Aug;43(2):453-6. doi: 10.1210/jcem-43-2-453.

DOI:10.1210/jcem-43-2-453
PMID:820711
Abstract

Plasma growth hormone (GH) levels were significantly increased following L-arginine (30 g) infusion or insulin (0.1 U/kg body wt)-induced hypoglycemia in normal men. When synthetic thyrotropin-releasing hormone (TRH) (1 mg) was infused intravenously for 150 min, beginning 30 min before arginine or insulin administration, GH responses to arginine and insulin were significantly blunted with a mean (+/- SE) percentage inhibition of 80.1 +/- 8.8% and 30.6 +/- 10.3%, respectively. These results suggest a possible inhibitory effect of TRH on GH secretion in man.

摘要

相似文献

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引用本文的文献

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Lack of effect of hexarelin on TRH-induced TSH response in normal adult man.在正常成年男性中，六肽生长激素释放肽对促甲状腺激素释放激素诱导的促甲状腺激素反应无影响。
J Endocrinol Invest. 1998 Apr;21(4):239-44. doi: 10.1007/BF03347309.
2
Thyrotropin-releasing hormone does not inhibit lysine vasopressin-induced growth hormone secretion in normal men.促甲状腺激素释放激素并不抑制正常男性中赖氨酸加压素诱导的生长激素分泌。
Experientia. 1985 Dec 15;41(12):1573-4. doi: 10.1007/BF01964813.
3
Inhibitory influence of thyrotropin releasing hormone administration on growth hormone response to low doses of growth hormone-releasing hormone in normal man.
促甲状腺激素释放激素给药对正常男性生长激素对低剂量生长激素释放激素反应的抑制作用。
J Endocrinol Invest. 1988 Jun;11(6):413-7. doi: 10.1007/BF03349071.
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Effect of simultaneous administration of GHRH (1-40) and TRH on GH, PRL and TSH secretion in normal man.正常人同时给予生长激素释放激素（1-40）和促甲状腺激素释放激素对生长激素、催乳素和促甲状腺激素分泌的影响。
J Endocrinol Invest. 1986 Dec;9(6):497-501. doi: 10.1007/BF03346973.
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