大鼠小脑GABAA/苯二氮䓬受体的亚基组成。
The subunit composition of a GABAA/benzodiazepine receptor from rat cerebellum.
作者信息
Khan Z U, Gutierrez A, De Blas A L
机构信息
Division of Molecular Biology and Biochemistry, School of Biological Sciences, University of Missouri-Kansas City 64110-2499.
出版信息
J Neurochem. 1994 Jul;63(1):371-4. doi: 10.1046/j.1471-4159.1994.63010371.x.
The pentameric subunit composition of a large population (36%) of the cerebellar granule cell GABAA receptors that show diazepam (or clonazepam)-insensitive [3H]Ro 15-4513 binding has been determined by immunoprecipitation with subunit-specific antibodies. These receptors have alpha 6, alpha 1, gamma 2S, gamma 2L, and beta 2 or beta 3 subunits colocalizing in the same receptor complex.
大量（36%）小脑颗粒细胞GABAA受体呈现出对二氮卓（或氯硝西泮）不敏感的[3H]Ro 15 - 4513结合，其五聚体亚基组成已通过亚基特异性抗体免疫沉淀法确定。这些受体具有α6、α1、γ2S、γ2L以及β2或β3亚基，它们共定位于同一受体复合物中。
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