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多杀性巴氏杆菌和溶血巴氏杆菌的铁供应

Iron supply of Pasteurella multocida and Pasteurella haemolytica.

作者信息

Reissbrodt R, Erler W, Winkelmann G

机构信息

Robert-Koch-Institut des Bundesgesundheitsamtes, Bereich Wernigerode, Germany.

出版信息

J Basic Microbiol. 1994;34(1):61-3. doi: 10.1002/jobm.3620340114.

DOI:10.1002/jobm.3620340114
PMID:8207666
Abstract

Pasteurella multocida and Pasteurella haemolytica do not produce hydroxamate- or phenolate type siderophores. However, transport- and utilization systems could be detected for the well known siderophores ferrioxamine B, E, G, rhizoferrin and the intermediate 2,3-dihydroxybenzoic acid by means of cross-feeding tests in both Pasteurella species. Enterobactin and ferrichrome did not feed any of the Pasteurella strains tested. Additionally, alpha-ketoacids and alpha-hydroxyacids such as pyruvic acid, alpha-hydroxyisovaleric acid and others acting as primary metabolites enabled growth of P. multocida and P. haemolytica under iron limitation.

摘要

多杀巴斯德氏菌和溶血巴斯德氏菌不产生异羟肟酸型或酚盐型铁载体。然而,通过在这两种巴斯德氏菌中进行交叉饲喂试验,可以检测到针对著名铁载体去铁胺B、E、G、根瘤菌素以及中间体2,3-二羟基苯甲酸的转运和利用系统。肠杆菌素和铁色素不能供食任何测试的巴斯德氏菌菌株。此外,α-酮酸和α-羟基酸,如丙酮酸、α-羟基异戊酸等作为初级代谢产物,能使多杀巴斯德氏菌和溶血巴斯德氏菌在铁限制条件下生长。

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Iron-regulated excretion of alpha-keto acids by Salmonella typhimurium.鼠伤寒沙门氏菌对α-酮酸的铁调节排泄
J Bacteriol. 1997 Jul;179(14):4538-44. doi: 10.1128/jb.179.14.4538-4544.1997.