Hein J
Institute of Biological Sciences, Aarhus University, Denmark.
J Theor Biol. 1994 Mar 21;167(2):169-74. doi: 10.1006/jtbi.1994.1062.
An algorithm is presented that aligns two DNA sequences minimizing the overall amount of evolution that the associated proteins have experienced. It is generalized to minimizing a weighted average of protein and DNA evolution.
提出了一种算法,该算法能使两个DNA序列对齐,从而使相关蛋白质经历的总体进化量最小化。该算法被推广到使蛋白质和DNA进化的加权平均值最小化。