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恒河猴(猕猴)脊髓损伤的神经解剖学分析。

A neuroanatomical analysis of spinal cord injury in the rhesus monkey (Macaca mulatta).

作者信息

Bresnahan J C, King J S, Martin G F, Yashon D

出版信息

J Neurol Sci. 1976 Aug;28(4):521-42. doi: 10.1016/0022-510x(76)90122-2.

Abstract

Thirteen rhesus monkeys were subjected to impacts of either 200, 300, 400, oe 500 g-cm, on the dorsal surface of the spinal cord (Allen 1911). Six monkeys served as controls to determine the results of transection of the cord as well as the optimal survival time, and 2 additional subjects underwent the operative procedures only. Most of the animals were sacrificed 1 week postoperatively and the brains and spinal cords were processed by the Fink and Heimer (1967) technique for degenerating axons. Two contrils and 1 experimental subject, sacrificed at 1 week, were prepared for electron-microscopic analysis...

摘要

13只恒河猴的脊髓背侧受到200、300、400或500克 - 厘米的撞击(艾伦,1911年)。6只猴子作为对照,以确定脊髓横断的结果以及最佳存活时间,另外2只动物仅接受手术操作。大多数动物在术后1周处死,其大脑和脊髓采用芬克和海默(1967年)的技术处理,以观察轴突退变情况。2只对照动物和1只在1周时处死的实验动物用于电子显微镜分析……

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