Wender M, Szczech J, Hoffmann S
Department of Neurology School of Medicine, Poznań, Poland.
Neuropatol Pol. 1993;31(1-2):17-24.
An analysis of heavy metals content in the brain of a clinically unusual case of hepatolenticular degeneration was performed with the use of paramagnetic resonance. The studies established a manyfold increase of copper content in the brain in the form of free ions, and, less significant, also in the form of copper multi-ion clusters. The content of iron in the studied brain was lower than in controls. These results confirmed significantly the neuropathological diagnosis of hepato-lenticular degeneration.
利用顺磁共振对肝豆状核变性临床特殊病例的大脑重金属含量进行了分析。研究发现，大脑中以游离离子形式存在的铜含量增加了许多倍，以铜多离子簇形式存在的铜含量增加幅度较小。所研究大脑中的铁含量低于对照组。这些结果显著证实了肝豆状核变性的神经病理学诊断。
