Liberman L, Giess C S, Dershaw D D, Louie D C, Deutch B M
Department of Radiology, Memorial Sloan-Kettering Cancer Center, New York, NY 10021.
Radiology. 1994 Jul;192(1):157-60. doi: 10.1148/radiology.192.1.8208929.
To determine the imaging characteristics of non-Hodgkin lymphoma (NHL) of the breast and correlate these findings with histopathologic subtype.
The authors retrospectively reviewed records in 32 cases of histologically proved NHL in 29 women. Mammography was performed before biopsy in all cases, and breast sonography was performed before biopsy in eight.
Mammary NHL was primary in 21 of the 32 cases (66%) and secondary in 11 (34%). Mammography revealed a solitary, uncalcified mass in 22 cases (69%), multiple masses in three (9%), and diffuse increased opacity with skin thickening in three (9%). Four cases (13%) had normal findings. Seven of the eight sonograms revealed masses, which were solitary in five and multiple in two. Histologic examination showed diffuse NHL in 26 cases (81%) and follicular NHL in six (19%). No mammographic or sonographic features were identified that helped distinguish primary from secondary disease or follicular from diffuse NHL.
Although the imaging characteristics may suggest the possibility of breast NHL, none of the findings are pathognomonic. The imaging pattern of mammary NHL is unrelated to its histopathologic subtype.
确定乳腺非霍奇金淋巴瘤（NHL）的影像学特征，并将这些发现与组织病理学亚型相关联。
作者回顾性分析了29例女性32例经组织学证实的NHL病例记录。所有病例均在活检前行乳腺钼靶检查，其中8例在活检前行乳腺超声检查。
32例中21例（66%）乳腺NHL为原发性，11例（34%）为继发性。乳腺钼靶检查显示22例（69%）为孤立性、无钙化肿块，3例（9%）为多发性肿块，3例（9%）为弥漫性密度增高伴皮肤增厚。4例（13%）检查结果正常。8例超声检查中有7例显示有肿块，其中5例为孤立性，2例为多发性。组织学检查显示26例（81%）为弥漫性NHL，6例（19%）为滤泡性NHL。未发现有助于区分原发性与继发性疾病或滤泡性与弥漫性NHL的钼靶或超声特征。
尽管影像学特征可能提示乳腺NHL的可能性，但没有一项发现具有确诊意义。乳腺NHL的影像学表现与其组织病理学亚型无关。
