Reinig J W, Stutley J E, Leonhardt C M, Spicer K M, Margolis M, Caldwell C B
Anne Arundel MRI, Annapolis, MD 21403.
Radiology. 1994 Jul;192(1):41-6. doi: 10.1148/radiology.192.1.8208962.
To determine the efficacy of various magnetic resonance (MR) imaging sequences for the differentiation of adrenal masses.
Fifty-three adrenal masses in 46 patients (adenomas, metastases, myelolipomas, hemorrhages, and pheochromocytomas) were evaluated by means of T1-, T2-, and T2*-weighted sequences, calculated T2 values, chemical shift imaging techniques, and dynamic contrast material-enhanced imaging. The Student t test and receiver operating characteristic analysis were used to evaluate the differences in the groups of masses.
Analysis of the chemical shift-induced signal intensity of the adrenal masses and the T2*-weighted sequence enabled differentiation of adenomas, metastases, and pheochromocytomas. Adenomas and pheochromocytomas were also differentiated by means of a heavily T2-weighted sequence. Signal intensity values for all masses overlapped.
Although a chemical shift imaging technique and a T2*-weighted sequence helped correctly differentiate among the groups of adrenal masses, the degree of overlap suggests that it is still difficult to evaluate disease in individual patients.
确定各种磁共振（MR）成像序列对肾上腺肿块的鉴别诊断效能。
对46例患者的53个肾上腺肿块（腺瘤、转移瘤、髓样脂肪瘤、出血及嗜铬细胞瘤）采用T1加权、T2加权和T2*加权序列、计算T2值、化学位移成像技术及动态对比剂增强成像进行评估。采用Student t检验和受试者操作特征分析评估肿块组间差异。
对肾上腺肿块化学位移诱导的信号强度及T2*加权序列分析可鉴别腺瘤、转移瘤和嗜铬细胞瘤。通过重T2加权序列也可鉴别腺瘤和嗜铬细胞瘤。所有肿块的信号强度值存在重叠。
尽管化学位移成像技术和T2*加权序列有助于正确区分肾上腺肿块组，但重叠程度表明对个体患者疾病的评估仍存在困难。
