Martin-Du Pan R C, Rouiller D, Goumaz M
Laboratoire Riotton, Genève.
Schweiz Med Wochenschr. 1994 May 14;124(19):806-9.
6 years after surgery for epidermoid lung cancer, a 58-year-old man presented with atopic dermatitis and a high level of IgE, primary hypothyroidism of autoimmune origin, slight hyperprolactinemia and adrenal insufficiency of pituitary origin. ACTH levels were low and unresponsive to CRH. There was no deficiency of the other pituitary hormones and the MRI of the pituitary was normal. The other instances of autoimmune thyroiditis associated with ACTH deficiency are reviewed. The etiology of the deficiency is discussed in the context of a possible hypophysitis.
一名58岁男性在接受表皮样肺癌手术后6年，出现特应性皮炎和高水平的IgE、自身免疫性原发性甲状腺功能减退、轻度高催乳素血症以及垂体源性肾上腺功能不全。促肾上腺皮质激素（ACTH）水平较低，且对促肾上腺皮质激素释放激素（CRH）无反应。其他垂体激素无缺乏，垂体MRI检查正常。本文回顾了其他与ACTH缺乏相关的自身免疫性甲状腺炎病例。在可能存在垂体炎的背景下讨论了该缺乏症的病因。
