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[一种快速比浊微量法用于测定不同年龄高血压患者的止血和纤溶紊乱情况]

[A rapid turbidimetric micromethod in the determination of hemostatic and fibrinolytic disorders in arterial hypertension patients of different ages].

作者信息

Sushko O O, Lezhen T I, Platonova T M, Chernishenko T M

出版信息

Lik Sprava. 1993 Jul(7):58-60.

PMID:8209534
Abstract

Disorders of haemostasis and fibrinolysis were studied in 54 patients of various age with arterial hypertension by turbidimetric express micromethod. Activation of coagulative system and inhibition of fibrinolytic activity tending to get more pronounced with age were found in patients with hypertonic disease at II stage and systolic arterial hypertension. Turbidimetry has considerable advantages: it can be performed rapidly, requires as much as 0.1 ml of plasma for the assay and provides complete information about the state of haemostasis and fibrinolysis. The method may be important in detecting minor signs of disseminated intravascular coagulation in patients with hypertonic disease.

摘要

采用比浊快速微量法对54例不同年龄的高血压患者的止血和纤溶紊乱情况进行了研究。在Ⅱ期高血压病和收缩期动脉高血压患者中发现,凝血系统激活和纤溶活性抑制随年龄增长有更明显的趋势。比浊法有相当多的优点:检测速度快,每次检测只需0.1 ml血浆,能提供有关止血和纤溶状态的完整信息。该方法对于检测高血压病患者弥散性血管内凝血的轻微迹象可能具有重要意义。

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