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经颅磁刺激。其在部分性癫痫患者评估中的作用。

Transcranial magnetic stimulation. Its role in the evaluation of patients with partial epilepsy.

作者信息

Jennum P, Winkel H

机构信息

Department of Clinical Neurophysiology, Hvidovre Hospital, Copenhagen, Denmark.

出版信息

Acta Neurol Scand Suppl. 1994;152:93-6. doi: 10.1111/j.1600-0404.1994.tb05195.x.

Abstract

Transcranial magnetic stimulation (TMS) is a relative new method in the evaluation of patients with various neurological diseases. With the introduction of repetitive (rapid rate) transcranial magnetic stimulators (RTMS), it has been possible to apply cortical stimuli with a stimulus rate up to 100 Hz. The preliminary results with TRMS suggest that it may be used in the study of speech lateralization. Seizures have been reported in patients with partial epilepsy during TMS. In these cases it remains uncertain whether the seizures were induced by the TMS or coincidentally with it. Minor changes in paroxysmal activity have been reported in some patients. These data suggest, that TMS is neither sensitive nor specific as an activation procedure of the epileptic focus in patients with partial epilepsy. Seizures have been provoked using RTMS, but its use as a seizure-inducing method is not yet evaluated.

摘要

经颅磁刺激(TMS)是评估各种神经系统疾病患者的一种相对较新的方法。随着重复性(快速率)经颅磁刺激器(RTMS)的引入,现在已经能够以高达100Hz的刺激速率施加皮质刺激。TRMS的初步结果表明,它可用于言语侧化研究。在TMS期间,部分癫痫患者已报告有癫痫发作。在这些病例中,癫痫发作是由TMS诱发还是与之巧合仍不确定。一些患者报告有阵发性活动的轻微变化。这些数据表明,对于部分癫痫患者,TMS作为癫痫病灶的激活程序既不敏感也不特异。使用RTMS已诱发癫痫发作,但其作为一种诱发癫痫发作的方法尚未得到评估。

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