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冠状病毒科现包含两个属,即冠状病毒属和环曲病毒属:冠状病毒科研究小组报告

The Coronaviridae now comprises two genera, coronavirus and torovirus: report of the Coronaviridae Study Group.

作者信息

Cavanagh D, Brian D A, Brinton M A, Enjuanes L, Holmes K V, Horzinek M C, Lai M M, Laude H, Plagemann P G, Siddell S G

机构信息

Division of Molecular Biology, AFRC Institute for Animal Health, Compton Laboratory, Newbury, UK.

出版信息

Adv Exp Med Biol. 1993;342:255-7. doi: 10.1007/978-1-4615-2996-5_39.

Abstract

At the April 1992, mid-term meeting of the International Committee on Taxonomy of Viruses (ICTV) a proposal from the Coronaviridae Study Group (CSG) to include the torovirus genus in the Coronaviridae was accepted. Following another proposal, the arterivirus genus was removed from the Togaviridae but not assigned to another family. The arteriviruses have some features in common with the Coronaviridae but also have major differences. After much debate, culminating in September 1992, it was decided that the CSG would not recommend inclusion of arterivirus in the Coronaviridae. It was agreed that (a) the nomenclature used for coronavirus genes, mRNAs and polypeptides (Cavanagh et al., 1990) should be used for toroviruses, (b) that the small (about 100 amino acids) membrane-associated protein, which is distinct from the integral membrane glycoprotein M, associated with virions of infectious bronchitis (Liu & Inglis, 1991) and transmissible gastroenteritis (Godet et al., 1992) coronaviruses would be referred to by the acronym sM (lower case 's') and (c) that 'pol' (polymerase) should be used as a working term for gene 1, which comprises open reading frames (ORFs) 1a and 1b in both genera of the Coronaviridae.

摘要

1992年4月,国际病毒分类委员会(ICTV)中期会议接受了冠状病毒研究小组(CSG)提出的将环曲病毒属纳入冠状病毒科的提议。根据另一项提议,动脉炎病毒属从披膜病毒科中移除,但未被归入另一科。动脉炎病毒与冠状病毒科有一些共同特征,但也有重大差异。经过多次辩论,最终在1992年9月决定,CSG不建议将动脉炎病毒纳入冠状病毒科。会议商定:(a) 用于冠状病毒基因、mRNA和多肽的命名法(卡瓦纳等人,1990年)应适用于环曲病毒;(b) 与传染性支气管炎(刘和英格利斯,1991年)和传染性胃肠炎(戈代等人,1992年)冠状病毒粒子相关的、与完整膜糖蛋白M不同的小(约100个氨基酸)膜相关蛋白,将用首字母缩写sM(小写's')表示;(c) “pol”(聚合酶)应用作基因1的工作术语,基因1在冠状病毒科的两个属中均包含开放阅读框(ORF)1a和1b。

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