肝转移瘤：钆螯合物增强动脉门静脉造影期间多层面快速低角度激发磁共振成像检测

Hepatic metastases: detection with multisection FLASH MR imaging during gadolinium chelate-enhanced arterial portography.

作者信息

Soyer P, Laissy J P, Sibert A, Azencot M, Vissuzaine C, Marmuse J P, Achour E, Hercot O, Menu Y

机构信息

Department of Radiology, Hopital Bichat, Paris, France.

出版信息

Radiology. 1993 Nov;189(2):401-5. doi: 10.1148/radiology.189.2.8210366.

DOI:10.1148/radiology.189.2.8210366

PMID:8210366

Abstract

PURPOSE

To determine the feasibility and sensitivity of multisection fast low-angle shot (FLASH) magnetic resonance (MR) imaging in the depiction of hepatic metastases.

MATERIALS AND METHODS

The cases of 10 patients with 39 surgically proved hepatic metastases were prospectively evaluated. After unenhanced T1- and T2-weighted spin-echo (SE) and FLASH imaging, 4 mL of a 0.5 mol/L solution of a gadolinium chelate (tetraazacyclododecanetetraacetic acid) was injected into the superior mesenteric artery during FLASH imaging in a single breath-holding period.

RESULTS

No side effects were noted. With multisection FLASH MR arterial portography, tumor-to-liver contrast-to-noise ratio (34.5 +/- 4.4) was significantly increased compared with unenhanced MR imaging. Sensitivity was 74% (29 of 39) for combined SE and multisection FLASH imaging and 95% (37 of 39) for multisection FLASH MR arterial portography (McNemar test, P < .02).

CONCLUSION

Multisection FLASH MR arterial portography is a safe, feasible, and sensitive technique with which to detect hepatic metastases.

摘要

目的

确定多层面快速低角度激发（FLASH）磁共振（MR）成像在显示肝转移瘤方面的可行性和敏感性。

材料与方法

前瞻性评估10例经手术证实有39个肝转移瘤患者的病例。在进行非增强T1加权和T2加权自旋回波（SE）以及FLASH成像后，在单次屏气期间的FLASH成像过程中，将4毫升0.5摩尔/升的钆螯合物（四氮杂环十二烷四乙酸）溶液注入肠系膜上动脉。

结果

未观察到副作用。通过多层面FLASH MR动脉门静脉造影，与非增强MR成像相比，肿瘤与肝脏的对比噪声比（34.5±4.4）显著增加。联合SE和多层面FLASH成像的敏感性为74%（39个中的29个），多层面FLASH MR动脉门静脉造影的敏感性为95%（39个中的37个）（McNemar检验，P<.02）。