Kaplan C
Department of Pathology, University Hospital, SUNY Stony Brook 11794-7025.
Semin Diagn Pathol. 1993 Aug;10(3):232-50.
Many viruses can infect the fetus in utero, by either ascending or hematogenous routes. Much is known about the maternal-fetal passage of virus from clinical, virologic, and serologic studies. Although transplacental passage is a key aspect of these infections, there is much more limited information about changes in the placenta. For a few infections, placental characteristics have been well described, and there is now increasing information on many others. Newer techniques for in situ demonstration of viruses will hopefully yield much information about diagnosis and the mechanisms of transplacental passage.
许多病毒可通过上行或血行途径在子宫内感染胎儿。从临床、病毒学和血清学研究中，我们对病毒的母婴传播已有很多了解。虽然胎盘传播是这些感染的一个关键方面，但关于胎盘变化的信息却更为有限。对于少数几种感染，胎盘特征已有详尽描述，而现在关于其他许多感染的信息也在不断增加。用于病毒原位检测的新技术有望提供大量关于诊断和胎盘传播机制的信息。
