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在严重胰腺功能不全的情况下,胰腺提取物对于元素性和聚合性肠内营养制剂的吸收是必需的。

Pancreatic extracts are necessary for the absorption of elemental and polymeric enteral diets in severe pancreatic insufficiency.

作者信息

Caliari S, Benini L, Bonfante F, Brentegani M T, Fioretta A, Vantini I

机构信息

Dept. of Gastroenterology, Rehabilitation Hospital of Verona University, Valeggio sul Mincio, Italy.

出版信息

Scand J Gastroenterol. 1993 Aug;28(8):749-52. doi: 10.3109/00365529309098285.

DOI:10.3109/00365529309098285
PMID:8210993
Abstract

Tube feeding nutrition, either elemental or polymeric, is increasingly used in patients with digestive problems. Pancreatic insufficiency is a widely accepted indication for the use of an elemental formula, which requires less residual digestive capacity. To confirm this assumption, we have compared the absorption of elemental and polymeric diets and the effect of exogenous pancreatic enzymes in a patient on long-term total enteral feeding after total pancreatectomy. Malabsorption of both formulas was observed without enzyme supplementation. A marked improvement of fat and nitrogen absorption was obtained when pancreatic enzymes were added to both enteral diets. It is concluded that pancreatic enzymes should always be added to liquid diets in pancreatic insufficiency. No clear advantage is to be anticipated by the use of elemental as compared with polymeric diets.

摘要

管饲营养,无论是要素型还是聚合型,在患有消化问题的患者中使用越来越普遍。胰腺功能不全是使用要素配方的一个广泛认可的指征,因为要素配方所需的残余消化能力较低。为了证实这一假设,我们比较了一名全胰切除术后长期接受全肠内营养患者对要素型和聚合型饮食的吸收情况以及外源性胰酶的作用。在未补充酶的情况下,两种配方均出现吸收不良。当在两种肠内饮食中添加胰酶后,脂肪和氮的吸收有显著改善。得出的结论是,在胰腺功能不全时,应始终在流质饮食中添加胰酶。与聚合型饮食相比,使用要素型饮食预计没有明显优势。

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引用本文的文献

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Exocrine pancreatic insufficiency in adults: a shared position statement of the Italian Association for the Study of the Pancreas.成人外分泌胰腺功能不全:意大利胰腺研究协会的联合立场声明。
World J Gastroenterol. 2013 Nov 28;19(44):7930-46. doi: 10.3748/wjg.v19.i44.7930.
2
Pancreatic enzyme therapy.胰酶治疗。
Dtsch Arztebl Int. 2010 Aug;108(34-35):578-82. doi: 10.3238/arztebl.2011.0578. Epub 2010 Aug 29.