Satoh H, Uozumi T, Arita K, Kurisu K, Hotta T, Kiya K, Ikawa F, Goishi J, Sogabe T
Department of Neurosurgery, Hiroshima University School of Medicine, Japan.
Surg Neurol. 1993 Nov;40(5):414-9. doi: 10.1016/0090-3019(93)90223-n.
Reports of spontaneous rupture of a craniopharyngioma cyst are extremely rare. Five cases of spontaneous rupture of a craniopharyngioma cysts are reported. Clinical symptoms included chemical meningitis in three patients, alleviation of headache in one, and improvement in a visual disturbance in one. Reduction in cyst size was confirmed by computed tomography or magnetic resonance imaging in three of five patients, and the histopathological diagnosis was confirmed histologically in four patients. Cerebrospinal fluid findings were abnormal in the three patients with chemical meningitis. Spontaneous rupture of craniopharyngioma cysts tended to occur more frequently in adult males. Computed tomography and magnetic resonance imaging were useful in diagnosing cyst rupture, and cerebrospinal fluid findings, especially the presence of cholesterol crystals and an elevated cholesterol concentration, are suggestive, even when no reduction in cyst size is observed radiologically.
颅咽管瘤囊肿自发性破裂的报道极为罕见。本文报告了5例颅咽管瘤囊肿自发性破裂的病例。临床症状包括3例患者出现化学性脑膜炎，1例头痛缓解，1例视力障碍改善。5例患者中有3例经计算机断层扫描或磁共振成像证实囊肿大小缩小，4例患者经组织病理学确诊。3例发生化学性脑膜炎的患者脑脊液检查结果异常。颅咽管瘤囊肿自发性破裂在成年男性中似乎更常发生。计算机断层扫描和磁共振成像有助于诊断囊肿破裂，脑脊液检查结果，尤其是胆固醇结晶的存在和胆固醇浓度升高，即使在影像学上未观察到囊肿大小缩小，也具有提示意义。
