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主动脉心室成形术减轻左心室流出道梗阻——96例患者的长期结果

Reduction of the left-ventricular outflow-tract obstruction by aortoventriculoplasty--long-term results of 96 patients.

作者信息

de Vivie E R, Borowski A, Mehlhorn U

机构信息

Clinic for Thoracic and Cardiovascular Surgery, University of Cologne, Germany.

出版信息

Thorac Cardiovasc Surg. 1993 Aug;41(4):216-23. doi: 10.1055/s-2007-1013858.

DOI:10.1055/s-2007-1013858
PMID:8211925
Abstract

The aortoventriculoplasty (AVP) is an established surgical procedure for enlargement of different types of congenital and acquired obstruction of the left-ventricular outflow tract (LVOTO), especially with narrowing of the aortic valvular and subvalvular segment. Between 1974 and 1992, 96 patients underwent AVP. There were 32 female and 64 male patients, aged 3 to 32 years (mean 11.2 +/- 2.7 years) at operation. Indications for the procedure were as follows: 1. narrowing of the aortic annulus (19 patients), 2. multi-level stenosis (26 patients), 3. "outgrown"-prosthesis (8 patients), 4. recurrent hypertrophic obstructive cardiomyopathy (HOCM) (5 patients), and 5. subaortic stenosis of different origins (38 patients; out of these 19 patients had a "tunnel-like" stenosis, 7 of them with a "Shone-complex"). Seventy-six patients had previous operations at different levels of the left-ventricular tract. The mean preoperative peak transvalvular gradient was 88 +/- 27 mmHg (range 50-160 mmHg) and could be reduced by AVP to 14 +/- 13 mmHg. The early mortality was 8.3% (8/96). Among the last 58 patients there were no deaths. Three patients underwent subsequent reoperations: one for ascending aortic aneurysm, one for right-ventricular outflow tract obstruction (RVOTO), and one for "outgrown" prosthesis. Three patients required pacemaker implantation for a permanent a-v block, 71 of 96 patients had sinus rhythm postoperatively. The long-term results are similar to those of standard aortic valve replacement in childhood and adolescents. The advantages and disadvantages of the AVP in comparison to the other alternative surgical methods for relief of LVOTO are discussed.

摘要

主动脉心室成形术(AVP)是一种成熟的外科手术,用于扩大不同类型的先天性和后天性左心室流出道梗阻(LVOTO),尤其是主动脉瓣及瓣下节段狭窄的情况。1974年至1992年间,96例患者接受了AVP手术。其中女性32例,男性64例,手术时年龄为3至32岁(平均11.2±2.7岁)。该手术的适应证如下:1. 主动脉瓣环狭窄(19例);2. 多级狭窄(26例);3. “生长过度”的假体(8例);4. 复发性肥厚性梗阻性心肌病(HOCM)(5例);5. 不同病因的主动脉瓣下狭窄(38例;其中19例为“隧道样”狭窄,7例合并“Shone复合征”)。76例患者此前在左心室道不同水平接受过手术。术前平均跨瓣峰值压差为88±27 mmHg(范围50 - 160 mmHg),通过AVP可降至14±13 mmHg。早期死亡率为8.3%(8/96)。在最后58例患者中无死亡病例。3例患者随后接受了再次手术:1例因升主动脉瘤,1例因右心室流出道梗阻(RVOTO),1例因“生长过度”的假体。3例患者因永久性房室传导阻滞需要植入起搏器,96例患者中有71例术后为窦性心律。长期结果与儿童及青少年标准主动脉瓣置换术相似。文中讨论了AVP与其他缓解LVOTO的替代手术方法相比的优缺点。

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