Schober K
Klinik und Poliklinik für kleine Haus- und Heimtiere, Veterinärmedizinischen Fakultät, Universität Leipzig.
Tierarztl Prax. 1993 Aug;21(4):349-54.
The determination of the intracellular acid-base state is reported in this paper, using erythrocytic haemolysate in dogs as an example. Reference values are given for 217 clinically healthy dogs. The effects of various selected stages of illness and additional stresses on the erythrocytic acid-base equilibrium are reported and compared with acid-base changes in the blood. The metabolic acidosis observed may occur earlier and be stronger in the intracellular space than in the blood. There seems to be a closer correlation between a disturbed intraerythrocytic acid-base equilibrium and the degree of clinical symptoms than between the (commonly investigated) acid-base changes in the blood and the clinical presentations. The investigation of the blood alone does not provide a satisfactory indication of the patient's acid-base state and of the necessity for treatment.
本文报道了以犬红细胞溶血产物为例的细胞内酸碱状态的测定。给出了217只临床健康犬的参考值。报告了疾病不同选定阶段及额外应激对红细胞酸碱平衡的影响，并与血液中的酸碱变化进行了比较。观察到的代谢性酸中毒在细胞内空间可能比在血液中出现得更早且更严重。红细胞内酸碱平衡紊乱与临床症状程度之间的相关性似乎比血液中（通常所研究的）酸碱变化与临床表现之间的相关性更密切。仅对血液进行检测并不能令人满意地表明患者的酸碱状态及治疗的必要性。
