Barbosa R M, Arilha M
Maternal and Child Health Division, Institute of Health, São Paulo, Brazil.
Stud Fam Plann. 1993 Jul-Aug;24(4):236-40.
Cytotec, the commercial name for misoprostol, which is a synthetic analogue of prostaglandin E1, was approved for use in Brazil in 1986 to treat gastric and duodenal ulcers. The drug can and has also been used to induce abortion, which has created controversy in a country in which induced abortion is illegal. A study of the drug was undertaken in 1992 that included analyses of the drug's sales profile, of information published by the media, and of its use from women's and gynecologists' points of view, the latter examined using qualitative methodologies. The analysis of Cytotec's sales volume showed quick growth from its introduction until the first half of 1991, when its use was restricted by the Ministry of Health. For women, Cytotec's main advantages have been that it is relatively inexpensive, convenient to use, and can be used in private. Data obtained from gynecologists show that Cytotec's addition to the obstetric therapeutic arsenal was welcome and also confirmed the drug's influence in reducing the complications of illegal abortions shown in other studies.
喜克溃是米索前列醇的商品名，米索前列醇是前列腺素E1的合成类似物，1986年在巴西被批准用于治疗胃溃疡和十二指肠溃疡。该药物能够且也已被用于诱导堕胎，这在一个堕胎违法的国家引发了争议。1992年对该药物进行了一项研究，其中包括对药物销售情况、媒体发布的信息以及从女性和妇科医生角度对其使用情况的分析，后者采用定性方法进行研究。对喜克溃销量的分析表明，从其引入到1991年上半年使用受到卫生部限制期间，销量增长迅速。对女性而言，喜克溃的主要优点在于其相对便宜、使用方便且可在私下使用。从妇科医生那里获得的数据表明，喜克溃被纳入产科治疗手段受到欢迎，同时也证实了该药物在减少其他研究中显示的非法堕胎并发症方面的影响。
